Buy 44-(2-Methylpropoxy)benzenemethanamine Hydrochloride Online – High-Purity Pharmaceutical Intermediate at chemikalstore.com

4-2-methylpropoxybenzenemethanamine-hydrochloride (4-(2-Methylpropoxy)benzenemethanamine hydrochloride) (CAS 37806-44-3) is a specialty amine salt and a vital intermediate for advanced pharmaceutical, chemical, and research applications. When you buy 4-(2-methylpropoxy)benzenemethanamine hydrochloride online at chemikalstore.com, you secure a high-purity compound with full documentation, batch traceability, and prompt India-wide delivery. This guide provides a complete technical and commercial profile, SEO-optimized for all key terms and tailored for industrial, laboratory, and R&D buyers.

What is 4-(2-Methylpropoxy)benzenemethanamine Hydrochloride?

4-(2-Methylpropoxy)benzenemethanamine hydrochloride is a white to off-white crystalline solid. It is a hydrochloride salt of 4-(2-methylpropoxy)benzenemethanamine, featuring a benzylamine core substituted at the para position with a 2-methylpropoxy group. This structure imparts both lipophilicity and reactivity, making it a valuable building block in the synthesis of pharmaceuticals, notably as an intermediate for pimavanserin, an antipsychotic drug

Key Chemical and Physical Properties

Applications of 4-(2-Methylpropoxy)benzenemethanamine Hydrochloride

1. Pharmaceutical Intermediate

• Pimavanserin Synthesis: This compound is a key intermediate in the synthesis of pimavanserin, an antipsychotic drug used for the treatment of Parkinson’s disease psychosis and schizophrenia

• Other CNS Drugs: Used in research and development of analogs for neuropsychiatric disorders.

2. Medicinal Chemistry and Drug Discovery

• Lead Optimization: The 2-methylpropoxy (isobutoxy) group is a common motif for improving CNS penetration and metabolic stability.

• SAR Studies: Used in structure-activity relationship (SAR) studies for new psychoactive and neuroactive agents.

3. Chemical Synthesis and Research

• Building Block: Used for the synthesis of substituted benzylamines, aryl ethers, and heterocyclic scaffolds.

• Reference Standard: Analytical standard for method development in pharmaceutical QC labs.

Synthetic and Reaction Chemistry

Typical Synthetic Route

1. Etherification: 4-hydroxybenzylamine is alkylated with 2-methylpropyl bromide or tosylate to yield 4-(2-methylpropoxy)benzylamine.

2. Salt Formation: The free amine is converted to the hydrochloride salt by bubbling HCl gas or adding aqueous HCl.

Reactivity

• Nucleophilic Substitution: The benzylamine group is reactive towards acylation, alkylation, and reductive amination.

• Salt Stability: The hydrochloride form stabilizes the amine, making it easier to handle and purify.

Technical Specifications and Quality Control

Safety, Handling, and Storage

Hazard Classification

• GHS: Not classified as hazardous under most regulations, but handle as a laboratory chemical

• Precautions: Avoid inhalation, ingestion, and contact with skin or eyes.

• PPE: Wear gloves, goggles, lab coat, and use in a fume hood.

First Aid

• Inhalation: Move to fresh air, seek medical attention if symptoms persist.

• Skin Contact: Wash with soap and water for 15 minutes.

• Eye Contact: Rinse with water for 15 minutes, seek medical advice.

• Ingestion: Rinse mouth, seek medical attention.

Storage and Disposal

• Store in a tightly sealed container at 2–8°C, dry, away from light and incompatible materials.

• Dispose of waste according to local hazardous waste regulations.

Comparison: 4-(2-Methylpropoxy)benzenemethanamine Hydrochloride vs. Related Compounds

How to Buy 4-(2-Methylpropoxy)benzenemethanamine Hydrochloride Online at chemikalstore.com

1. Visit chemikalstore.com and search for “4-(2-methylpropoxy)benzenemethanamine hydrochloride online”.

2. Review product details: Purity, batch size, documentation, and price.

3. Enquire or order online: Use the enquiry form for custom or bulk pricing.

4. Secure checkout: Multiple payment options, GST invoicing, and shipment tracking.

5. Receive COA and MSDS: With every batch for regulatory compliance and quality assurance.

Frequently Asked Questions (FAQ)

Q1: What is the main use of 4-(2-methylpropoxy)benzenemethanamine hydrochloride?
A: It is a key intermediate in the synthesis of pimavanserin, an antipsychotic drug, and is also used in CNS drug research and advanced organic synthesis

Q2: What is the shelf life and storage condition?
A: Store at 2–8°C in a tightly sealed container. Shelf life is typically 24 months when stored properly.

Q3: Is this compound suitable for pharmaceutical manufacturing?
A: Yes, provided it meets ≥98% purity and is accompanied by COA and MSDS for regulatory compliance.

Q4: Can I get custom or bulk packaging?
A: Yes, chemikalstore.com offers custom and bulk packaging for research, pilot, and industrial needs.

Q5: What documentation is provided?
A: Each batch comes with a COA, MSDS, and analytical data (HPLC, NMR) for regulatory and quality assurance.

Q6: Is this product available for export?
A: Yes, international shipping is available with all required documentation.

Global Market and Supplier Insights

• chemikalstore.com – India-wide and international supply, bulk and lab packs, technical support.

• Other global suppliers: Sigma-Aldrich, TCI, Fisher Scientific, LGC Standards, CanbiPharm, Chemball

• Price Range: $100–$500 per 10g–100g, depending on purity and quantity.

• Regulatory Note: For R&D use only; not for human consumption or drug formulation without further processing and regulatory approvals.

Summary Table: 4-(2-Methylpropoxy)benzenemethanamine Hydrochloride