Buy bistriphenylphosphinepalladiumii-dichloride Bis(triphenylphosphine)palladium(II) Dichloride Online – High-Purity Pd(II) Catalyst for Advanced Organic Synthesis at chemikalstore.com

bistriphenylphosphinepalladiumii-dichloride Bis(triphenylphosphine)palladium(II) dichloride (CAS 13965-03-2), also abbreviated as PdCl₂(PPh₃)₂, is a palladium complex employed in cross-coupling and C–C/C–N bonding studies in organic, pharmaceutical, and material science research. By purchasing bis(triphenylphosphine)palladium(II) dichloride at chemikalstore.com you get a high-purity, research grade catalyst documented, batch traceable and delivered immediately throughout India.

Product Overview and Chemical Properties

Structure and Reactivity

• Square Planar Geometry: Pd(II) center was coordinated to two triphenylphosphine ligands and two chloride ligands in a trans arrangement.

• Ligand Lability: PPh₃ ligands are readily displaced, allowing the in situ generation of very active Pd(0) species.

• Stable Solid: Stable in the ambient condition; moisture and heat sensitive, and should be stored under the inert atmosphere

Catalytic and Synthetic Applications

1. Cross-Coupling Reactions

PdCl₂(PPh₃)₂ is the catalyst of choice for a wide range of C–C and C–N bond-forming reactions:

• Suzuki–Miyaura Coupling: Aryl halides + boronic acids → biaryls

• Heck Reaction: Aryl halides + alkenes → substituted alkenes

• Sonogashira Coupling: Aryl halides + alkynes → arylalkynes

• Stille Coupling: Aryl halides + organostannanes → biaryls

• Buchwald–Hartwig Amination: Aryl halides + amines → arylamines

• Negishi Coupling: Aryl halides + organozincs → biaryls/alkenes

• Hiyama Coupling: Aryl halides + organosilanes → biaryls

2. Advanced Synthesis and Method Development

• One-Pot Multistep Synthesis: The method allows tandem and cascade reactions to be carried out to assemble complex molecules.

• Heterocycle Synthesis: State of the art in the synthesis of indoles, furans and quinolines among other heterocyclic scaffolds.

• Polymer and Material Science: Polymer and material science is applied in the production of functionalized polymers, OLEDs and advanced materials.

3. Pharmaceutical and Fine Chemical Manufacturing

• API Synthesis: Critical for C–C and C–N couplings in drug development and scale-up.

• Agrochemicals: Synthesis of pesticides, herbicides, and fungicides.

• Custom Ligand Complexes: Precursor for a wide range of functionalized Pd(II) and Pd(0) complexes.

Technical Specifications and Quality Control

Comparison: PdCl₂(PPh₃)₂ vs. Other Palladium Catalysts

Safety, Handling, and Storage

Hazard Classification (GHS/CLP)

• H302: Harmful if swallowed

• H315: Causes skin irritation

• H317: May cause allergic skin reaction

• H319: Causes serious eye irritation

• H335: May cause respiratory irritation

• H411: Toxic to aquatic life with long-lasting effects

NFPA Ratings: Health = 2, Fire = 1, Reactivity = 1

Precautions

• Use gloves, goggles, and lab coat.

• Avoid inhalation, ingestion, and skin/eye contact.

• Handle in a fume hood if dust is generated.

First Aid

• Skin/Eye Contact: Rinse with water for 15 minutes, seek medical attention if irritation persists.

• Inhalation: Move to fresh air, seek help if symptoms persist.

• Ingestion: Rinse mouth, do not induce vomiting, get medical help.

Storage and Disposal

• Store tightly sealed, in a dry, cool place at 2–10°C, under inert gas.

• Avoid exposure to moisture and heat.

• Dispose of waste according to local hazardous waste regulations.

Regulatory and Market Insights

• REACH, FDA, and ICH Q3D: Pharmaceutical and fine chemical applications, palladium residues must be low and have to be traceable. Batches of GMP and ISO are available in global markets.

• Environmental Impact: PdCl₂(PPh₃)₂ like all palladium catalysts is considered harmful to aquatic organisms and should be properly handled and disposed of responsibly.

• Market Trends: Pharma (38% of global use), fine chemicals, and advanced materials are the driving force of demand. Indian and Chinese suppliers are leading exporters with the European and Japanese suppliers specializing in the high-purity and low-impurity grades.

How to Buy Bis(triphenylphosphine)palladium(II) Dichloride Online at chemikalstore.com

1. Visit chemikalstore.com and search for “bis(triphenylphosphine)palladium(II) dichloride online”.

2. Review product details: Purity, batch size, documentation, and price.

3. Enquire or order online: Apply the enquiry form in individual or bulk prices.

4. Secure checkout: Various payment methods, GST invoicing and tracking of shipments.

5. Receive COA and MSDS: With every batch for regulatory compliance and quality assurance.

Packaging and Supply Options

All shipments include COA, MSDS, and batch traceability. Custom and bulk packaging available.

Frequently Asked Questions (FAQ)

Q1: What is the shelf life of bis(triphenylphosphine)palladium(II) dichloride?
A: 24–36 months when stored under inert gas at 2–10°C, protected from moisture and heat

Q2: Is it suitable for pharmaceutical manufacturing?
A: Yes, as long as it is ≥98% pure and supplied with COA and MSDS so that it is regulated. GMP grade available on request

Q3: What solvents is it soluble in?
A: chloroform, toluene, benzene; and cannot be dissolved in water

Q4: Can it be used for Suzuki, Heck, and Sonogashira reactions?
A: Yes, it is a pre-catalyst of choice of these and numerous other cross-coupling reactions

Q5: What documentation is provided?
A: The shipments will contain COA, MSDS and analytical data (HPLC, NMR, elemental) to comply with the regulatory and quality standards..

Q6: Is it available for export?
A: Yes, chemikalstore.com delivers internationally with all the necessary papers.

Summary Table