Buy 44-(2-Methylpropoxy)benzenemethanamine Hydrochloride Online – High-Purity Pharmaceutical Intermediate at chemikalstore.com

4-2-methylpropoxybenzo methanamine hydrochloride (CAS 37806-44-3) is a specialty amine salt and a critical intermediate in the high technology of pharmaceutical, chemical and research. With chemikalstore.com, shopping on the internet, you are guaranteed to receive a high-purity compound that is well documented, can be traced back to batches and is delivered in no more than a few days, nationwide. This manual offers a full technical and commercial profile, search engine optimized on all of the main keywords and focused on industrial, laboratory, and research and development purchasers.

What is 4-(2-Methylpropoxy)benzenemethanamine Hydrochloride?

4- (2-Methylpropoxy) benzene methylanamine hydrochloride is an off-white crystalline solid. It is a hydrochloride salt of 4 -(2-methylpropoxy)benzenemethanamine, which comprises a benzylamine core with the para substituted by 2-methylpropoxy. This structure gives it lipophilicity and reactivity, which has been useful in the synthesis of pharmaceuticals particularly in the production of pimavanserin, an antipsychotic drug.

Key Chemical and Physical Properties

Applications of 4-(2-Methylpropoxy)benzenemethanamine Hydrochloride

1. Pharmaceutical Intermediate

• Pimavanserin Synthesis: Pimavanserin is one of the major intermediates of the synthesis of pimavanserin, a type of antipsychotic medicine, which is used in treating the psychosis of Parkinson and schizophrenic disease.

• Other CNS Drugs: Applied in the neuropsychiatric disorder analog research and development.

2. Medicinal Chemistry and Drug Discovery

• Lead Optimization: The 2-methylpropoxy (isobutoxy) functional group has been used as a popular CNS-penetrating/metabolic-stabilizing moiety.

• SAR Studies: SAR Studies are used in structure-activity relationship (SAR) studies of new psychoactive and neuroactive drugs.

3. Chemical Synthesis and Research

• Building Block: Applied in the production of substituted benzylamine, aryl ethers as well as heterocyclic scaffolds.

• Reference Standard: Method development analytical standard of pharmaceutical QC Labs.

Synthetic and Reaction Chemistry

Typical Synthetic Route

1. Etherification: 4-hydroxybenzylamine is alkylated with 2-methylpropyl bromide or tosylate to produce 4 ( 2 -methylpropoxy)benzylamine.

2. Salt Formation: The free amine is transformed into the hydrochloride salt by either the bubbling of the HCl gas or with the use of aqueous HCl.

Reactivity

• Nucleophilic Substitution: The benzylamine functional group is reactive to acylation, alkylation, and reduction amino.

• Salt Stability: The hydrochloride is more stable than the amine and it is easier to work with and purify.

Technical Specifications and Quality Control

Safety, Handling, and Storage

Hazard Classification

• GHS: Not classified as hazardous under most regulations, but handle as a laboratory chemical

• Precautions: Avoid inhalation, ingestion, and contact with skin or eyes.

• PPE: Wear gloves, goggles, lab coat, and use in a fume hood.

First Aid

• Inhalation: Move to fresh air, seek medical attention if symptoms persist.

• Skin Contact: Wash with soap and water for 15 minutes.

• Eye Contact: Rinse with water for 15 minutes, seek medical advice.

• Ingestion: Rinse mouth, seek medical attention.

Storage and Disposal

• Store in a tightly sealed container at 2–8°C, dry, away from light and incompatible materials.

• Dispose of waste according to local hazardous waste regulations.

Comparison: 4-(2-Methylpropoxy)benzenemethanamine Hydrochloride vs. Related Compounds

How to Buy 4-(2-Methylpropoxy)benzenemethanamine Hydrochloride Online at chemikalstore.com

1. Go online to chemikalstore.com and enter the name of the product 4-(2-methylpropoxy)benzenemethanamine hydrochloride.

2. Check product specifications: Purity, lot size, records and cost.

3. Order or ask online: Custom or bulk pricing needs to be done using the enquiry form.

4. Protected checkout: Various payment systems, GST invoicing and shipment tracking.

5. Take COA and MSDS: With each batch to ensure compliance and quality assurance to the regulations.

Frequently Asked Questions (FAQ)

Q1: What is the main use of 4-(2-methylpropoxy)benzenemethanamine hydrochloride?
A: It is one of the first intermediates of the synthesis of pimavanserin, which is an antipsychotic medication, as well as in the CNS drug studies and high-performance organic synthesis.

Q2: What is the shelf life and storage condition?
A: Store at 2–8°C in a tightly sealed container. Shelf life is typically 24 months when stored properly.

Q3: Is this compound suitable for pharmaceutical manufacturing?
A: Yes, provided it meets ≥98% purity and is accompanied by COA and MSDS for regulatory compliance.

Q4: Can I get custom or bulk packaging?
A: Yes, chemikalstore.com offers custom and bulk packaging for research, pilot, and industrial needs.

Q5: What documentation is provided?
A: Each batch will be accompanied with a COA, MSDS and analytical data (HPLC, NMR) as a quality and regulatory assurance.

Q6: Is this product available for export?
A: Yes, there is international shipping provided with all the necessary papers.

Global Market and Supplier Insights

• chemikalstore.com – India-wide and international supply, bulk and lab packs, technical support.

• Other global suppliers: Sigma-Aldrich, TCI, Fisher Scientific, LGC Standards, CanbiPharm, Chemball

• Price Range: $100–$500 per 10g–100g, depending on purity and quantity.

• Regulatory Note: For R&D use only; not for human consumption or drug formulation without further processing and regulatory approvals.

Summary Table: 4-(2-Methylpropoxy)benzenemethanamine Hydrochloride