Buy bistriphenylphosphinepalladiumii-dichloride Bis(triphenylphosphine)palladium(II) Dichloride Online – High-Purity Pd(II) Catalyst for Advanced Organic Synthesis at chemikalstore.com

bistriphenylphosphinepalladiumii-dichloride Bis(triphenylphosphine)palladium(II) dichloride (CAS 13965-03-2), commonly written as PdCl₂(PPh₃)₂, is a gold-standard palladium complex for cross-coupling and C–C/C–N bond formation in organic, pharmaceutical, and material science research. When you buy bis(triphenylphosphine)palladium(II) dichloride online at chemikalstore.com, you secure a high-purity, research-grade catalyst with full documentation, batch traceability, and prompt India-wide delivery.

Product Overview and Chemical Properties

Structure and Reactivity

• Square Planar Geometry: Pd(II) center coordinated to two chloride and two triphenylphosphine ligands in a trans configuration.

• Ligand Lability: The PPh₃ ligands are easily displaced, enabling in situ formation of highly active Pd(0) species.

• Stable Solid: Chemically stable under ambient conditions; moisture and heat sensitive, best stored under inert atmosphere

Catalytic and Synthetic Applications

1. Cross-Coupling Reactions

PdCl₂(PPh₃)₂ is the catalyst of choice for a wide range of C–C and C–N bond-forming reactions:

• Suzuki–Miyaura Coupling: Aryl halides + boronic acids → biaryls

• Heck Reaction: Aryl halides + alkenes → substituted alkenes

• Sonogashira Coupling: Aryl halides + alkynes → arylalkynes

• Stille Coupling: Aryl halides + organostannanes → biaryls

• Buchwald–Hartwig Amination: Aryl halides + amines → arylamines

• Negishi Coupling: Aryl halides + organozincs → biaryls/alkenes

• Hiyama Coupling: Aryl halides + organosilanes → biaryls

2. Advanced Synthesis and Method Development

• One-Pot Multistep Synthesis: Enables tandem and cascade reactions for complex molecule assembly.

• Heterocycle Synthesis: Key in the preparation of indoles, furans, quinolines, and other heterocyclic scaffolds.

• Polymer and Material Science: Used in the synthesis of functionalized polymers, OLEDs, and advanced materials.

3. Pharmaceutical and Fine Chemical Manufacturing

• API Synthesis: Critical for C–C and C–N couplings in drug development and scale-up.

• Agrochemicals: Synthesis of pesticides, herbicides, and fungicides.

• Custom Ligand Complexes: Precursor for a wide range of functionalized Pd(II) and Pd(0) complexes.

Technical Specifications and Quality Control

Comparison: PdCl₂(PPh₃)₂ vs. Other Palladium Catalysts

Safety, Handling, and Storage

Hazard Classification (GHS/CLP)

• H302: Harmful if swallowed

• H315: Causes skin irritation

• H317: May cause allergic skin reaction

• H319: Causes serious eye irritation

• H335: May cause respiratory irritation

• H411: Toxic to aquatic life with long-lasting effects

NFPA Ratings: Health = 2, Fire = 1, Reactivity = 18

Precautions

• Use gloves, goggles, and lab coat.

• Avoid inhalation, ingestion, and skin/eye contact.

• Handle in a fume hood if dust is generated.

First Aid

• Skin/Eye Contact: Rinse with water for 15 minutes, seek medical attention if irritation persists.

• Inhalation: Move to fresh air, seek help if symptoms persist.

• Ingestion: Rinse mouth, do not induce vomiting, get medical help.

Storage and Disposal

• Store tightly sealed, in a dry, cool place at 2–10°C, under inert gas.

• Avoid exposure to moisture and heat.

• Dispose of waste according to local hazardous waste regulations.

Regulatory and Market Insights

• REACH, FDA, and ICH Q3D: Pharmaceutical and fine chemical applications require ultra-low palladium residues and full traceability. Global suppliers offer GMP and ISO-certified batches for regulated markets

• Environmental Impact: Like all palladium catalysts, PdCl₂(PPh₃)₂ is classified as hazardous to aquatic life and must be handled and disposed of responsibly

• Market Trends: Demand is driven by pharma (38% of global use), fine chemicals, and advanced materials. Indian and Chinese suppliers are major exporters, with European and Japanese suppliers focusing on high-purity, low-impurity grades

How to Buy Bis(triphenylphosphine)palladium(II) Dichloride Online at chemikalstore.com

1. Visit chemikalstore.com and search for “bis(triphenylphosphine)palladium(II) dichloride online”.

2. Review product details: Purity, batch size, documentation, and price.

3. Enquire or order online: Use the enquiry form for custom or bulk pricing.

4. Secure checkout: Multiple payment options, GST invoicing, and shipment tracking.

5. Receive COA and MSDS: With every batch for regulatory compliance and quality assurance.

Packaging and Supply Options

All shipments include COA, MSDS, and batch traceability. Custom and bulk packaging available.

Frequently Asked Questions (FAQ)

Q1: What is the shelf life of bis(triphenylphosphine)palladium(II) dichloride?
A: 24–36 months when stored under inert gas at 2–10°C, protected from moisture and heat

Q2: Is it suitable for pharmaceutical manufacturing?
A: Yes, provided it meets ≥98% purity and is accompanied by COA and MSDS for regulatory compliance. GMP-grade available on request

Q3: What solvents is it soluble in?
A: Chloroform, toluene, benzene; insoluble in water

Q4: Can it be used for Suzuki, Heck, and Sonogashira reactions?
A: Yes, it is a preferred Pd(II) pre-catalyst for these and many other cross-coupling reactions

Q5: What documentation is provided?
A: Each shipment includes COA, MSDS, and analytical data (HPLC, NMR, elemental) for regulatory and quality assurance.

Q6: Is it available for export?
A: Yes, chemikalstore.com ships internationally with all required documentation.

Summary Table